Detection of calcified tissue in the carotid artery by dental x-rays is not enough evidence to estimate a patient’s stroke risk was the conclusion of a systematic literature review published in this month’s Journal of the American Dental Association (JADA).

Stroke is one of the leading causes of death and disability among adults in the U.S. It occurs when a blood vessel that brings oxygen and nutrients to the brain bursts or becomes clogged by a blood clot or some other mass. Panoramic radiography is a procedure used in dental practice for detecting dental disease. According to the JADA article authors, a trend toward using panoramic x-rays to identify stroke-prone patients has become a much-debated health care issue over the past two decades.

In their literature review, the authors conducted an electronic search using 11 databases to evaluate evidence that links calcified carotid artery atheroma (CCAA) detection on panoramic radiographs and the precipitation of cerebrovascular accidents (CVA). The search identified 54 articles for the review. Only one study satisfied the authors’ inclusion criteria and found no significant difference in the incidence of cerebrovascular diseases between subjects with CCAA and subjects without CCAA.

This issue is complicated because there are many risk factors that predispose a person to generalized atherosclerosis and plaque formation that also can promote the risk of cerebrovascular blockage and stroke, according to the article. Incidental findings of CCAA on panoramic radiographs, the authors wrote, should not be the only basis for estimating risk of stroke. Risk factors such as age, smoking history, total cholesterol level, systolic blood pressure and hypertension should receive close examination.

Panoramic radiography may demonstrate that CCAAs calcify over time, but there is little evidence-based information that CCAAs are risk predictors for the diagnosis of cerebrovascular disease, they concluded.

“Further research is warranted before any recommendations can be made for or clinical guidelines developed regarding CCAAs detected on panoramic radiographs to predict a cerebrovascular accident,” the authors wrote.

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Note: Journalists wishing to receive a copy of the April 2007 Journal of the American Dental Association study, “Calcified Carotid Artery Atheroma and Stroke: A Systematic Review,” should contact ADA media relations at (312) 440-2806 or .(JavaScript must be enabled to view this email address).

Contact: Fred Peterson
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312-440-2806
American Dental Association