Grapefruit can Cause Unintended Effects

Buspirone (BuSpar) interacts with GRAPEFRUIT
Grapefruit juice might increase how much buspirone (BuSpar) the body absorbs. Drinking grapefruit juice while taking buspirone (BuSpar) might increase the effects and side effects of buspirone (BuSpar).

Carbamazepine (Tegretol) interacts with GRAPEFRUIT
Grapefruit juice might increase how much carbamazepine (Tegretol) the body absorbs. Drinking grapefruit juice while taking carbamazepine (Tegretol) might increase the effects and side effects of carbamazepine (Tegretol).

Carvedilol (Coreg) interacts with GRAPEFRUIT
The body breaks down carvedilol (Coreg) to get rid of it. Grapefruit juice seems to decrease how quickly the body breaks down carvedilol (Coreg). Drinking grapefruit juice while taking carvedilol (Coreg) might increase the effects and side effects of carvedilol (Coreg).

Cisapride (Propulsid) interacts with GRAPEFRUIT
Grapefruit juice might decrease how quickly the body gets rid of cisapride (Propulsid). Drinking grapefruit juice while taking cisapride (Propulsid) might increase the effects and side effects of cisapride (Propulsid).

Clomipramine (Anafranil) interacts with GRAPEFRUIT
The body breaks down clomipramine (Anafranil) to get rid of it. Grapefruit juice might decrease how quickly the body gets rid of clomipramine (Anafranil). Taking grapefruit juice along with clomipramine (Anafranil) might increase the effects and side effects of clomipramine (Anafranil).

Cyclosporine (Neoral, Sandimmune) interacts with GRAPEFRUIT
Grapefruit might increase how much cyclosporine (Neoral, Sandimmune) the body absorbs. Drinking grapefruit juice while taking cyclosporine (Neoral, Sandimmune) might increase the side effects of cyclosporine.

Dextromethorphan (Robitussin DM, and others) interacts with GRAPEFRUIT
The body breaks down dextromethorphan (Robitussin DM, others) to get rid of it. Grapefruit might decrease how quickly the body breaks down dextromethorphan (Robitussin DM, others). Drinking grapefruit juice while taking dextromethorphan (Robitussin DM, others) might increase the effects and side effects of dextromethorphan (Robitussin DM, others).

Estrogens interacts with GRAPEFRUIT
The body breaks down estrogens to get rid of them. Grapefruit juice seems to decrease how quickly the body breaks down estrogens and increase how much estrogen the body absorbs. Drinking grapefruit juice while taking estrogens might increase estrogen levels and side effects associated with estrogen such as breast cancer.

Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol (Climara, Vivelle, Estring), and others.

Etoposide (VePesid) interacts with GRAPEFRUIT
Grapefruit might decrease how much etoposide (VePesid) the body absorbs. Drinking grapefruit juice while taking etoposide (VePesid) might decrease the effectiveness of etoposide (VePesid).

Itraconazole (Sporanox) interacts with GRAPEFRUIT
Itraconazole (Sporanox) is used to treat fungal infections. Grapefruit juice might decrease how much itraconazole (Sporanox) the body absorbs. Drinking grapefruit juice while taking itraconazole (Sporanox) might decrease the effectiveness of Itraconazole (Sporanox). Do not drink grapefruit juice if you are taking Itraconazole (Sporanox).

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with GRAPEFRUIT
Some medications are changed and broken down by the liver.

Grapefruit juice might decrease how quickly the liver breaks down some medications. Drinking grapefruit juice while taking some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking grapefruit, talk to your healthcare provider if you are taking any medications that are changed by the liver.

Some medications changed by the liver include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and many others.

Medications for high blood pressure (Calcium channel blockers) interacts with GRAPEFRUIT
Grapefruit juice might increase how much medication for high blood pressure the body absorbs. Drinking grapefruit juice while taking some medications for high blood pressure might cause your blood pressure to go too low.

Some medications for high blood pressure include nifedipine (Adalat, Procardia), verapamil (Calan, Isoptin, Verelan), diltiazem (Cardizem), isradipine (DynaCirc), felodipine (Plendil), amlodipine (Norvasc), and others.

Medications used for lowering cholesterol (Statins) interacts with GRAPEFRUIT
The body breaks down some medications used for lowering cholesterol to get rid of them. Grapefruit juice might decrease how quickly the body breaks down some medications used for lowering cholesterol. Drinking grapefruit juice while taking some medications used for lowering cholesterol might increase the effects and side effects of these medications.

Some medications used for High cholesterol include lovastatin (Mevacor), simvastatin (Zocor), atorvastatin (Lipitor), cerivastatin (Baycol), and others.

However, grapefruit juice doesn’t seem to affect pravastatin (Pravachol).

Methylprednisolone interacts with GRAPEFRUIT
The body breaks down methylprednisolone to get rid of it. Grapefruit juice can decrease how quickly the body gets rid of methylprednisolone. Drinking grapefruit juice while taking methylprednisolone might increase the effects and side effects of methylprednisolone.

Praziquantel (Biltricide) interacts with GRAPEFRUIT
The body breaks down praziquantel (Biltricide) to get rid of it. Grapefruit juice can decrease how quickly the body breaks down praziquantel (Biltricide). Drinking grapefruit juice while taking praziquantel (Biltricide) might increase the effects and side effects of praziquantel (Biltricide).

Quinidine interacts with GRAPEFRUIT
The body breaks down quinidine to get rid of it. Grapefruit juice might decrease how fast the body gets rid of quinidine. Drinking grapefruit juice while taking quinidine might increase the chance of side effects.

Scopolamine (Transderm Scop) interacts with GRAPEFRUIT
The body breaks down scopolamine to get rid of it. Grapefruit juice can decrease how fast the body breaks down scopolamine. Drinking grapefruit juice while taking scopolamine might increase the effects and side effects of scopolamine.

Sedative medications (Benzodiazepines) interacts with GRAPEFRUIT
Sedative medications can cause sleepiness and drowsiness. Grapefruit juice can decrease how quickly the body breaks down some medications. Drinking grapefruit juice while taking some sedative medications can increase the effects and side effects of some sedative medications.

Some sedative medications that might interact with grapefruit juice include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others.

Sildenafil (Viagra) interacts with GRAPEFRUIT
The body breaks down sildenafil (Viagra) to get rid of it. Grapefruit can decrease how quickly the body breaks down sildenafil (Viagra). Drinking grapefruit juice while taking sildenafil (Viagra) can increase the effects and side effects of sildenafil.

Terfenadine (Seldane) interacts with GRAPEFRUIT
Grapefruit can increase how much terfenadine (Seldane) that the body absorbs. Drinking grapefruit juice while taking terfenadine (Seldane) might increase the effects and side effects of terfenadine (Seldane).

This information comes from a press release by the FDA, published in February of 2012.


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By: Christopher McClorey

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Provided by ArmMed Media