Eating a Mediterranean diet and following national recommendations for physical activity are each associated with a reduced risk of death over a five-year period, according to two reports in the December 10/24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. Both studies use data from the National Institutes of Health-AARP Diet and Health Study, which began when questionnaires were returned from 566,407 AARP members age 50 to 71 in six states between 1995 and 1996.

In one study, Panagiota N. Mitrou, Ph.D., then of the National Cancer Institute, Bethesda, Md., and now of the University of Cambridge, England, and colleagues used a nine-point scale to assess conformity with the Mediterranean diet in 380,296 of the participants (214,284 men and 166,012 women) with no history of chronic disease.

Components of the diet included vegetables, legumes, fruits, nuts, whole grains, fish, ratio of monounsaturated fats, alcohol and meat. During five years of follow-up, 12,105 participants died, including 5,985 from cancer and 3,451 from cardiovascular disease. Those with higher Mediterranean diet scores were less likely to die of any cause or of cancer or heart disease.

In another study, Michael F. Leitzmann, M.D., Dr.P.H., also of the National Cancer Institute, and colleagues analyzed the results of two questionnaires on physical activity from 252,925 of the participants (142,828 men and 110,097 women). Of those, 7,900 died during follow-up. Compared with being inactive, individuals who performed the amount of moderate physical activity recommended in national guidelines (at least 30 minutes most days of the week) were 27 percent less likely to die and those who achieved the goal for vigorous physical activity (at least 20 minutes three times per week) were 32 percent less likely to die. Smaller amounts of physical activity also appeared to be associated with a 19 percent reduced risk of death.

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(Arch Intern Med. 2007;167(22):2461-2468 and 2453-2460. Available pre-embargo to the media at http://www.jamamedia.org.)

Editor’s Note: Please see the articles for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.
Contact: Panagiota N. Mitrou, Ph.D.
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