What advances are driving clinical applications of tissue engineering and regenerative medicine?

Explosive growth in the field of tissue engineering and regenerative medicine has led to innovative and promising applications and techniques, many of which are now being tested in human clinical trials. Hot topics, research advances, and transformative publications that are driving the field forward are highlighted in a comprehensive overview of the field presented in Tissue Engineering, Part B, Reviews, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

Matthew Fisher, PhD and Robert Mauck, PhD, Perelman School of Medicine, University of Pennsylvania, and Philadelphia Veterans Administration Medical Center, Philadelphia, PA, identify four key areas in which the field is progressing. The first main theme, in the area of tissue engineering, focuses on advances in grafts and materials, including human or animal tissue from which the cells are removed and the remaining scaffold is used to regenerate new tissues, as well as scaffolds made of new types of biomaterials. Second, in the field of regenerative medicine, the authors highlight the role of novel scaffolds and various growth and control factors in promoting tissue formation and, for example, bone healing.

In the article “Tissue Engineering and Regenerative Medicine: Recent Innovations and the Transition to Translation,” the authors identify two additional areas that signal progress in the field: the increasing number of applications advancing into clinical trials; and the growing use of novel types of cells, such as induced pluripotent stem cells.

“Considering the rapid pace of growth and development in regenerative medicine, it is imperative that we fully consider recent advances,” says Reviews Co-Editor-in-Chief John P. Fisher, PhD, Professor and Associate Chair, Fischell Department of Bioengineering, University of Maryland, College Park, MD. “Dr. Matthew Fisher and Dr. Robert Mauck have wonderfully reviewed the efforts in the tissue engineering field over the past few years, highlighting advances in biomaterials, cell-based constructs, and translational endeavors.”

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About the Journal
Tissue Engineering is an authoritative peer-reviewed journal published monthly in print and online in three parts: Part A—the flagship journal; Part B - Reviews; and Part C - Methods. Led by Co-Editors-In-Chief Antonios Mikos, PhD, Louis Calder Professor at Rice University, Houston, TX, and Peter C. Johnson, MD, Vice President, Research and Development, Avery Dennison Medical Solutions of Chicago, IL and President and CEO, Scintellix, LLC, Raleigh, NC, the Journal brings together scientific and medical experts in the fields of biomedical engineering, material science, molecular and cellular biology, and genetic engineering. Tissue Engineering is the Official Journal of the Tissue Engineering & Regenerative Medicine International Society (TERMIS). Complete tables of content and a sample issue may be viewed on the Tissue Engineering website.

About the Publisher
Mary Ann Liebert, Inc. publishers, is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Stem Cells and Development, Human Gene Therapy and HGT Methods, and Advances in Wound Care. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry’s most widely read publication worldwide. A complete list of the firm’s 70 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc. publishers website.

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Mary Ann Liebert, Inc. 140 Huguenot St., New Rochelle, NY 10801-5215
Phone: (914) 740-2100 (800) M-LIEBERT Fax: (914) 740-2101

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Mary Ann Liebert, Inc./Genetic Engineering News

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