Epidermoid carcinoma of the anal canal is an uncommon disease, and most institutions have only a small series of patients. The current study of a large series of patients treated with…

Cancers of the anal canal are a rare and diverse group of tumors of the gastrointestinal tract currently managed most often with surgery, chemoradiotherapy,…

Anal canal cancers are rare, accounting for about 10% of cancers in the anorectal region and approximately 4,500 cases annually in the United States. Beginning in the early 1980s, the traditional management of abdominoperineal…

Anal intraepithelial neoplasia (AIN) as a precursor for invasive SCCA has emerged from the recent literature as one of the most important contributions to the field of anal…

While small tumours (<2 cm)  arising in the anal canal may be amenable to local excision, most patients present with lesions of greater dimensions. Thanks to the pioneering work of Nigro, it is now…

Carcinoma of the anus is a rare malignancy that usually is diagnosed at an advanced stage, in spite of being easily visible and accessible. Its treatment has evolved from being mainly surgical to one consisting…

The most common anorectal cancer is adenocarcinoma. Squamous cell (nonkeratinizing squamous cell or basaloid) carcinoma of the anorectum accounts for 3 to 5% of distal large-bowel cancers. Basal cell carcinoma, Bowen’s disease (intradermal carcinoma), extramammary…

Carcinoma of the anus represents about 2% of cancers of the large bowel. From 1950 to 1970, 20 patients were treated for this condition. Included were 113 patients with squamous cell carcinoma (31…

These tumors are relatively rare, comprising only 1-2% of all cancers of the anus and large intestine. Squamous cancers make up the majority of anal cancers. Squamous cancer involving the anal canal may…