Hereditary nonpolyposis colorectal carcinoma (HNPCC) is an autosomal dominant disorder responsible for 3 to 5% of cases of colorectal cancer. Symptoms, initial diagnosis, and treatment are similar to other forms of colorectal cancer.…

Carcinoma of the anus is a rare malignancy that usually is diagnosed at an advanced stage, in spite of being easily visible and accessible. Its treatment has evolved from being mainly surgical to one consisting…

Adenomas of the colon constitute the great majority of polypoid lesions. The World Health Organization (WHO) has classified adenomas as (1) tubular, (2) villous, and (3) tubulovillous. Adenomas may be sessile,…

Relevant Physiology and Pathophysiology

Epidemiology and Incidence. A striking feature of colonic cancer is its geographic variation in incidence. The disease seems to occur primarily in industrialized Western countries. In the…

Most benign small intestinal tumors cause no symptoms and are incidentally found during radiographic or endoscopic examination, surgery, or autopsy.

Adenomas may be polypoid or sessile, similar to their colonic counterparts.…

Relevant Physiology and Pathophysiology
Carcinoid tumors are an interesting group of neoplasms that have their origin in the endocrine argentaffin cells in the small intestinal mucosa (argentaffinomas). They…

Relevant Physiology and Pathophysiology

That malignant tumors of the small intestine are quite uncommon is surprising considering the much higher frequency of malignancies originating in the large intestine and stomach. Liquidity…