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New analysis of a drug approved for osteoporosis prevention and treatment has provided definitive evidence that the medication is also effective as a breast cancer…

The decision to screen women for breast cancer is based on the importance of the disease as a public health problem and the demonstrated ability of screening tests to meet acceptable…

The search for alternative methods of screening for breast cancer is stimulated by a desire to increase accuracy and to overcome some of the technical barriers associated with film screen mammography. We do not…

The usefulness of mammography is dependent on the proper use of dedicated mammography equipment, the diagnostic skills of the interpreter, and assessing and diminishing barriers to its regular use. These issues have been and are…

By convention, in the United States, most guidelines for breast cancer screening recommend that women begin screening at age 40 or at some time in their 40s. Guidelines that recommend screening beginning at…

The interpretation of a screening examination ultimately falls into one of two categories: normal or abnormal. These judgments, in turn, ultimately are divided among four categories based on either the determination…

Following are brief summaries of the major randomized trials of breast cancer screening. They represent study designs in which a large group of women was randomly assigned to a group that either would…

Evaluation of Breast Cancer Screening
The efficacy of a screening test is best evaluated with a population-based, randomized clinical trial with a mortality end point. Randomized trials eliminate the potential biases…

The decision to screen an asymptomatic population for preclinical disease is based on well-established, although not specific, criteria that relate to the disease in question and the characteristics of applicable screening test(s). The…

The importance of detecting localized breast cancer was recognized in the mid-eighteenth century by Henri Francois LeDran, who proposed that breast cancer originated as a localized disease that subsequently spread via…

A multicenter team of researchers has identified a panel of proteins linked to early development of pancreatic cancer in mice that applies also to early stages…

London, UK: Researchers are harnessing the powers of digital communications technology to help young cancer patients at home manage the side-effects caused by chemotherapy.

They…

Researchers believe they have found a compound produced by aggressive prostate tumors and hope they can use it to design a urine test to detect the most dangerous tumors, they…

British scientists said on Tuesday they had identified subtle chemical changes that allow abnormal cells to multiply out of control, a finding that could help detect colon cancer…

A research abstract that will be presented on Monday at SLEEP 2008, the 22nd Annual Meeting of the Associated Professional Sleep Societies (APSS), finds that poor sleep…

A substantial proportion of rectal cancer patients are receiving inappropriate surgical care, because of wide variations in practice across England, reveals research published ahead of print in…

Approaches for the primary prevention of breast cancer according to period of life are discussed here briefly and are considered in more detail elsewhere. Although the major reasons for the high rates of…

As noted in the first section of this chapter, the search for specific breast cancer risk factors has been stimulated by the large differences in rates of breast…

Much is known about the behavioral factors that influence breast cancer risk, and the links between these factors and the pathophysiology of the disease are becoming clearer. Known and suspected risk factors are described in…

A review of 115 studies conducted between 1971 and 1994 found little support for an association between specific occupations and breast cancer risk. Limited evidencesuggested that cosmetologists, beauticians,…

Evidence of geographic variation in incidence and mortality rates of breast cancer within the United States, the steady increase in incidence over time, and the identification of suspected breast cancer clusters have stimulated interest in…

Ionizing radiation to the chest in moderate to high doses (e.g., 1 to 3 Gy) at a young age substantially increases breast cancer risk. Among survivors of the atomic bombing of Hiroshima and Nagasaki, breast…

Regular physical activity has been hypothesized to prevent breast cancer, largely by reducing circulating levels of sex hormones. The mechanisms by which physical activity reduces exposure to hormones vary by period of life. Young girls…