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In the USA, endometrial cancer is the most common gynecologic malignancy and the fourth most common malignancy in women after breast, colorectal, and lung cancer. About 34,000 new cases of endometrial cancer were diagnosed in…

The fallopian tube is the least common site of cancer in the female genital tract, although its epithelial surface far exceeds that of the ovary, where epithelial cancer is 20 times more…

Carcinoma of the cervix was once the most common cause of cancer death in women, but over the past 30 years, the mortality rate has decreased by 50% due to widespread screening with the Pap…

Incidence and Epidemiology 
Epithelial ovarian cancer is the leading cause of death from gynecologic cancer in the United States. In 2004, 25,580 new cases were diagnosed and 16,090 women died from ovarian cancer.…

Fewer than 5% of all ovarian tumors are germ cell in origin. They include teratoma, dysgerminoma, endodermal sinus tumor, and embryonal carcinoma. Germ cell tumors of the ovary generally occur in younger women…

Carcinoma of the endometrium is the most common female pelvic malignancy. Approximately 40,300 new cases are diagnosed yearly, although in most (75%), tumor is confined to the uterine corpus at diagnosis and therefore most can…

Gestational trophoblastic diseases are a group of interrelated diseases that form a spectrum from benign hydatidiform mole to trophoblastic malignancy (placental-site trophoblastic tumor and choriocarcinoma). Malignant forms account for <1% of female gynecologic malignancies…

Researchers at Montefiore Medical Center are leading a nationwide clinical trial to determine whether a new genetic test can be used to personalize treatment for early-stage breast cancer.

According to a new study, women who gain weight in adulthood face a higher lifetime risk of all types of breast cancer even if they…

Lung cancer death rates are not higher among women than men who have never smoked, but death rates from lung cancer may be higher in African-American than Caucasian female never…

A new Mayo Clinic study reviewed CT scans of pancreatic cancer patients done before their cancer diagnosis and found that the cancer rapidly progresses from early to advanced stage in…

Selenium, an essential dietary mineral that can act as an antioxidant when incorporated into proteins, has been shown in many studies to reduce the incidence of cancers - notably lung, colorectal…

Women who gain weight as adults face a higher lifetime risk of all types of breast cancer, researchers reported on Monday.

The study adds to a large body of evidence…

Despite the ease and availability of Internet searches, cancer patients looking for information about their disease found more information by seeking help from a librarian than by searching on their own,…

Researchers at Mount Sinai School of Medicine have found that an improved version of the non-invasive fecal DNA (fDNA) test to screen for colon cancer (CRC) demonstrates a higher…

The incidence of melanoma, the most serious and deadly type of skin cancer, is increasing. In the United States, the lifetime risk of developing melanoma is now about one in 70. It…

Successful treatment of cancer requires elimination of all cancer cells, whether at the primary site, extended to local-regional areas, or metastatic to other regions of the body. The major modalities of therapy are…

Understanding of the mechanisms involved in the induction of immunity and the recognition of antigens by effector cells has improved dramatically in the past decade as molecular biology has joined forces with classic tumor immunology.…

TAAs can be useful tumor markers in the diagnosis and management of various tumors. An ideal tumor marker is released only from tumor tissue, is specific for a given tumor type (to direct diagnostic assessment),…

Interferons (IFNs) derived from WBCs (IFN-α- and IFN-γ) or from fibroblasts (IFN-β) or synthesized in bacteria by recombinant genetic techniques are glycoproteins that have antitumor and antiviral activity, which may originate partially from immunologically mediated…

Immunotherapy for cancer is best thought of as part of a broader subject, namely biologic therapy, or the application of biologic-response modifiers (BRMs). These agents can act through one or more mechanisms (1) to stimulate the…

As reported in the June 1 issue of Genes and Development, Drs. Katerina Politi, Harold Varmus and colleagues at the Memorial Sloan Kettering Cancer Center in New York have developed a…