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Many survivors of childhood cancer are not getting the optimal follow-up care recommended for detecting the long-term consequences of cancer treatment, according to a study of Canadian patients.

Though the…

Carcinoma of the Prostate - Incidence & Epidemiology
Prostate cancer is the most common cancer diagnosed and is the second leading cause of cancer death in American men. Of all cancers,…

Grading & Staging

The Gleason grading system is the most commonly employed grading system in the United States. It is truly a system that relies upon the low-power appearance of the glandular…

Patterns of Progression

The pattern of CaP progression has been well defined. The likelihood of local extension outside the prostate (extracapsular extension) or seminal vesicle invasion and distant metastases increases with…

Clinical Findings

A. Symptoms
Most patients with early-stage CaP are asymptomatic. The presence of symptoms often suggests locally advanced or metastatic disease. Obstructive or irritative voiding complaints can result from local growth…

Differential Diagnosis

Not all patients with an elevated PSA concentration have CaP. Other factors that elevate serum PSA include BPH, urethral instrumentation, infection, prostatic infarction, or vigorous prostate massage. Induration of the prostate…

Treatment

A. Localized Disease
1. General considerations - The optimal form of therapy for all stages of CaP remains a subject of great debate. Well-designed, randomized trials comparing various modalities for…

Women who use statin drugs to lower their cholesterol are no more likely to develop breast cancer than women who do not use the drugs, U.S. researchers reported on Tuesday.

Elderly women with early-stage breast cancer had a lower risk of recurrence when they were treated with radiation therapy, according to a study in the Journal…

Women who have never smoked are no more likely to die from lung cancer than male non-smokers - despite conventional wisdom otherwise, U.S. researchers reported on Tuesday.

In fact,…

Researchers at The University of Texas M. D. Anderson Cancer Center have received a $2.4 million grant from the National Cancer Institute to study…

Voluntary exercise and a restricted diet reduced the number and size of pre-cancerous polyps in the intestines of male mice and improved survival, according to a study by a University…

An Oregon Health & Science University Cancer Institute research laboratory has developed a novel mouse model designed specifically to study the often devastating head and neck squamous…

Male deaths in Britain from melanoma skin cancer have risen 31 percent in the past decade to more than 1,000 a year, according to figures released on Tuesday.

Dentists and physicians who take advantage of routine checkups to screen their high-risk patients for oral cancer may be the most cost-effective guard against the disease, at least in…

While doctors and scientists have long agreed that physical activity has health benefits, Rutgers cancer researcher Allan Conney and his New Jersey colleagues have found that exercise can even protect against skin…

Women with larger breasts have a greater risk of developing breast cancer before menopause than smaller-breasted women do, a new study shows.

While the findings are useful for breast cancer…

The hunt to find common genes that are associated with cancer is unlikely to be successful, say experts in this week’s British Medical Journal.

Huge resources are being invested…

Glivec (imatinib), which has dramatically improved survival prospects for some cancer patients, can interfere with bone development, according to U.S. researchers.

Results of a study published this week in The New…

Breast cancer is an understudied and poorly understood disease in Hispanic/Latina populations in the U.S., and breast cancer appears to be presenting at an earlier age in…

Although the incidence of thyroid cancer has more than doubled in the past 30 years, the rise is being attributed to improved diagnostic techniques of previously…

Researchers at New York University’s Courant Institute of Mathematical Sciences have developed a new algorithm that enhances the ability to detect a cancer gene, and have applied their algorithm to…

The blood of patients with head and neck cancer appears to have unique patterns of protein expression that one day could serve as a screening test for…

Bone mineral density, a measure of bone thickness, decreases during the first 2 years of androgen deprivation therapy in men with prostate cancer, according to a report in The Journal…