Breast Cancer | Benign Breast Diseases |

Benign Breast Diseases: Classification, Diagnosis, and Management

 Jun 16, 2008 Viewed: 9328

Merih Guray, Aysegul A. Sahin
University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA

Aysegul Sahin, M.D., University of Texas M. D. Anderson Cancer Center, Unit 85, 1515 Holcombe Boulevard, Houston, Texas 77030, USA. Telephone: 713-794-1500; Fax: 713-745-5704; e-mail: .(JavaScript must be enabled to view this email address)


References

  1. Caleffi M, Filho DD, Borghetti K et al. Cryoablation of benign breast tumors: evolution of technique and technology. Breast 2004;13:397-407.
  2. Kelsey JL, Gammon MD. Epidemiology of breast cancer. Epidemiol Rev 1990;12:228-240.
  3. Cole P, Mark Elwood J, Kaplan SD. Incidence rates and risk factors of benign breast neoplasms. Am J Epidemiol 1978;108:112-120.
  4. Hutchinson WB, Thomas DB, Hamlin WB et al. Risk of breast cancer in women with benign breast lesion. J Natl Cancer Inst 1980;65:13-20.
  5. Fitzgibbons PL, Henson DE, Hutter RV. Benign breast changes and the risk for subsequent breast cancer: an update of the 1985 consensus statement. Cancer Committee of the College of American Pathologists. Arch Pathol Lab Med 1998;122:1053-1055.
  6. Sarnelli R, Squartini F. Fibrocystic condition and "at risk" lesions in asymptomatic breasts: a morphologic study of postmenopausal women. Clin Exp Obstet Gynecol 1991;18:271-279.
  7. Bartow SA, Pathak DR, Black WC et al. Prevalence of benign, atypical, and malignant breast lesions in populations at different risk for breast cancer. A forensic autopsy study. Cancer 1987;60:2751-2760.
  8. Cook MG, Rohan TE. The patho-epidemiology of benign proliferative epithelial disorders of the female breast. J Pathol 1985;146:1-15.
  9. La Vecchia C, Parazzini F, Franceschi S et al. Risk factors for benign breast disease and their relation with breast cancer risk. Pooled information from epidemiologic studies. Tumori 1985;71:167-178.
  10. Donegan WL. Common benign conditions of the breast. In: Donegan WL, Spratt JS, eds. Cancer of the Breast, Fifth Edition. St. Louis, MO: Saunders, 2002:67-110.
  11. Shaaban AM, Sloane JP, West CS et al. Histopathologic types of benign breast lesions and risk of breast cancer. Am J Surg Pathol 2002;26: 421-430.
  12. Morrow M. Pre-cancerous breast lesions: implications for breast cancer prevention trials. Int J Radiat Oncol Biol Phys 1992;23:1071-1078.
  13. London SJ, Connolly JL, Schnitt SJ et al. A prospective study of benign breast disease and the risk of breast cancer. JAMA 1992;267:941-944.
  14. McDivitt RW, Stevens JA, Lee NC et al. Histologic types of benign breast disease and the risk for breast cancer. Cancer 1992;69:1408-1414.
  15. Pfeifer JD, Barr RJ, Wick MR. Ectopic breast tissue and breast-like sweat gland metaplasias: an overlapping spectrum of lesions. J Cutan Pathol 1999;26:190-196.
  16. Marshall MB, Moynihan JJ, Frost A et al. Ectopic breast cancer: case report and literature review. Surg Oncol 1994;3:295-304.
  17. O'Hara MF, Page DL. Adenomas of the breast and ectopic breast under lactational influences. Hum Pathol 1985;16:707-712.
  18. Markopoulos C, Kouskos E, Kontzoglou K et al. Breast cancer in ectopic breast tissue. Eur J Gynaecol Oncol 2001;22:157-159.
  19. Schinzel A. Ulnar-mammary syndrome. J Med Genet 1987;24:778-781.
  20. Tamiolakis D, Venizelos I, Antoniou C et al. Breast cancer development in a female with Poland's syndrome. Onkologie 2004;27:569-571.
  21. Fan W, Huang X, Chen C et al. TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines. Cancer Res 2004;64:5132-5139.
  22. Swerdlow AJ, Hermon C, Jacobs PA et al. Mortality and cancer incidence in persons with numerical sex chromosome abnormalities: a cohort study. Ann Hum Genet 2001;65:177-188.
  23. Rosen PP, ed. Chapter 2. Abnormalities of mammary growth and development. In: Rosen's Breast Pathology, Second Edition. Philadelphia: Lippincott Williams & Wilkins, 2001:23-27.
  24. Foxman B, D'Arcy H, Gillespie B et al. Lactation mastitis: occurrence and medical management among 946 breastfeeding women in the United States. Am J Epidemiol 2002;155:103-114.
  25. Michie C, Lockie F, Lynn W. The challenge of mastitis. Arch Dis Child 2003;88:818-821.
  26. Dener C, Inan A. Breast abscesses in lactating women. World J Surg 2003;27:130-133.
  27. Barbosa-Cesnik C, Schwartz K, Foxman B. Lactation mastitis. JAMA 2003;289:1609-1612.
  28. Erhan Y, Veral A, Kara E et al. A clinicopathologic study of a rare clinical entity mimicking breast carcinoma: idiopathic granulomatous mastitis. Breast 2000;9:52-56.
  29. Diesing D, Axt-Fliedner R, Hornung D et al. Granulomatous mastitis. Arch Gynecol Obstet 2004;269:233-236.
  30. Tewari M, Shukla HS. Breast tuberculosis: diagnosis, clinical features & management. Indian J Med Res 2005;122:103-110.
  31. Azlina AF, Ariza Z, Arni T et al. Chronic granulomatous mastitis: diagnostic and therapeutic considerations. World J Surg 2003;27:515-518.
  32. van Diest PJ, Beekman WH, Hage JJ. Pathology of silicone leakage from breast implants. J Clin Pathol 1998;51:493-497.
  33. Passaro ME, Broughan TA, Sebek BA et al. Lactiferous fistula. J Am Coll Surg 1994;178:29-32.
  34. Rosen PP, ed. Chapter 4. Specific infections. In: Rosen's Breast Pathology, Second Edition. Philadelphia: Lippincott Williams & Wilkins, 2001: 65-75.
  35. Furlong AJ, al-Nakib L, Knox WF et al. Periductal inflammation and cigarette smoke. J Am Coll Surg 1994;179:417-420.
  36. Rahal RMS, de Freitas-Junior R, Paulinelli RR. Risk factors for duct ectasia. Breast J 2005;11:262-265.
  37. Dixon JM, Ravisekar O, Chetty U et al. Periductal mastitis and duct ectasia:differentconditionswithdifferentaetiologies.BrJSurg 1996;83:820-822.
  38. Sweeney DJ, Wylie EJ. Mammographic appearances of mammary duct ectasia that mimic carcinoma in a screening programme. Australas Radiol 1995;39:18-23.
  39. Sakorafas GH. Nipple discharge: current diagnostic and therapeutic approaches. Cancer Treat Rev 2001;27:275-282.
  40. Rosai J, ed. Chapter 20. Breast. In: Rosai and Ackerman's Surgical Pathology, Ninth Edition. Philadelphia: Mosby, 2004:1763-1876.
  41. Kinoshita T, Yashiro N, Yoshigi J et al. Fat necrosis of breast: a potential pitfall in breast MRI. Clin Imaging 2002;26:250-253.
  42. Pullyblank AM, Davies JD, Basten J et al. Fat necrosis of the female breast--Hadfield re-visited. Breast 2001;10:388-391.
  43. Silverberg SG, Masood S. The breast. In: Silverberg SG, DeLellis RA, Frable WJ, eds. Principles and Practice of Surgical Pathology and Cytopathology, Third Edition. New York: Churchill-Livingstone, Inc., 1997:575-673.
  44. Rosen PP, ed. Chapter 3. Inflammatory and reactive tumors. In: Rosen's Breast Pathology, Second Edition. Philadelphia: Lippincott Williams & Wilkins, 2001:29-63.
  45. Love SM, Gelman RS, Silen W. Fibrocystic "disease" of the breast--a non-disease? N Engl J Med 1982;307:1010-1014.
  46. Santen RJ, Mansel R. Benign breast disorders. N Engl J Med 2005;353:275-285.
  47. Vorherr H. Fibrocystic breast disease: pathophysiology, pathomorphology, clinical picture, and management. Am J Obstet Gynecol 1986;154:161-179.
  48. Dupont WD, Page DL. Risk factors for breast cancer in women with proliferative breast disease. N Engl J Med 1985;312:146-151.
  49. Dupont WD, Parl FF, Hartmann WH et al. Breast cancer risk associated with proliferative breast disease and atypical hyperplasia. Cancer 1993;71:1258-1265.
  50. Palli D, Rosselli Del Turco M, Simoncini R et al. Benign breast disease and breast cancer: a case-control study in a cohort in Italy. Int J Cancer 1991;47:703-706.
  51. Hartmann LC, Sellers TA, Frost MH et al. Benign breast disease and the risk of breast cancer. N Engl J Med 2005;353:229-237.
  52. Marshall LM, Hunter DJ, Connolly JL et al. Risk of breast cancer associated with atypical hyperplasia of lobular and ductal types. Cancer Epidemiol Biomarkers Prev 1997;6:297-301.
  53. O'Malley FP, Bane AL. The spectrum of apocrine lesions of the breast. Adv Anat Pathol 2004;11:1-9.
  54. Houssami N, Irwig L, Ung O. Review of complex breast cysts: implications for cancer detection and clinical practice. ANZJ Surg 2005;75:1080-1085.
  55. Venta LA, Kim JP, Pelloski CE et al. Management of complex breast cysts. AJR Am J Roentgenol 1999;173:1331-1336.
  56. Vargas HI, Vargas MP, Gonzalez KD et al. Outcomes of sonography-based management of breast cysts. Am J Surg 2004;188:443-447.
  57. Lee K, Chan JKC, Gwi E. Tubular adenosis of the breast: a distinctive benign lesion mimicking invasive carcinoma. Am J Surg Pathol 1996;20:46-54.
  58. Jensen RA, Page DL, Dupont WD et al. Invasive breast cancer risk in women with sclerosing adenosis. Cancer 1989;64:1977-1983.
  59. Gill HK, Ioffe OB, Berg WA. When is a diagnosis of sclerosing adenosis acceptable at core biopsy? Radiology 2003;228:50-57.
  60. Bodian CA, Perzin KH, Lattes R et al. Prognostic significance of benign proliferative breast disease. Cancer 1993;71:3896-3907.
  61. Millis RR, Eusebi V. Microglandular adenosis of the breast. Adv Anat Pathol 1995;2:10-18.
  62. Eusebi V, Foschini MP, Betts CM et al. Microglandular adenosis, apocrine adenosis, and tubular carcinoma of the breast: an immunohistochemical comparison. Am J Surg Pathol 1993;17:99-109.
  63. Acs G, Simpson JF, Bleiweiss IJ et al. Microglandular adenosis with transition into adenoid cystic carcinoma of the breast. Am J Surg Pathol 2003;27:1052-1060.
  64. Tavassoli FA, ed. Chapter 5. Benign lesions. In: Pathology of the Breast, Second Edition. Stamford, CT: Appleton & Lange, 1999:115-204.
  65. Vina M, Wells CA. Clear cell metaplasia of the breast: a lesion showing eccrine differentiation. Histopathology 1989;15:85-92.
  66. Tavassoli FA, ed. Chapter 6. Ductal intraepithelial neoplasia. In: Pathology of the Breast, Second Edition. CT: Appleton & Lange, 1999:205-323.
  67. Koerner FC. Epithelial proliferations of ductal type. Semin Diagn Pathol 2004;21:10-17.
  68. Pinder SE, Ellis IO. The diagnosis and management of pre-invasive breast disease: ductal carcinoma in situ (DCIS) and atypical ductal hyperplasia (ADH)--current definitions and classification. Breast Cancer Res 2003;5:254-257.
  69. Webb PM, Byrne C, Schnitt SJ et al. Family history of breast cancer, age, and benign breast disease. Int J Cancer 2002;100:375-378.
  70. Page DL, Dupont WD, Rogers LW et al. Atypical hyperplastic lesions of the female breast. A long-term follow-up study. Cancer 1985;55:2698-2708.
  71. Tavassoli FA, Norris HJ. A comparison of the results of long-term follow-up for atypical intraductal hyperplasia and intraductal hyperplasia of the breast. Cancer 1990;65:518-529.
  72. Collins L, Baer H, Tamimi R et al. Magnitude and laterality of breast cancer risk in women with atypical hyperplasia of ductal and lobular types. Lab Invest 2006;86(suppl 1):24A.
  73. Dupont WD, Page DL. Relative risk of breast cancer varies with time since diagnosis of atypical hyperplasia. Hum Pathol 1989;20:723-725.
  74. Page DL, Schuyler PA, Dupont WD et al. Atypical lobular hyperplasia as a unilateral predictor of breast cancer risk: a retrospective cohort study. Lancet 2003;361:125-129.
  75. Schnitt SJ, Vincent-Salomon A. Columnar cell lesions of the breast. Adv Anat Pathol 2003;10:113-124.
  76. Schnitt SJ. The diagnosis and management of pre-invasive breast disease: flat epithelial atypia - classification, pathologic features and clinical significance. Breast Cancer Res 2003;5:263-268.
  77. Nasser SM. Columnar cell lesions: current classification and controversies. Semin Diagn Pathol 2004;21:18-24.
  78. Kennedy M, Masterson AV, Kerin M et al. Pathology and clinical relevance of radial scars: a review. J Clin Pathol 2003;56:721-724.
  79. Patterson JA, Scott M, Anderson N et al. Radial scar, complex sclerosing lesion and risk of breast cancer. Analysis of 175 cases in Northern Ireland. Eur J Surg Oncol 2004;30:1065-1068.
  80. Rabban JT, Sgroi DC. Sclerosing lesions of the breast. Semin Diagn Pathol 2004;21:42-47.
  81. Nielsen M, Christensen L, Andersen J. Radial scars in women with breast cancer. Cancer 1987;59:1019-1025.
  82. Jacobs TW, Byrne C, Colditz G et al. Radial scars in benign breast-biopsy specimens and the risk of breast cancer. N Engl J Med 1999;340:430-436.
  83. Fasih T, Jain M, Shrimankar J et al. All radial scars/complex sclerosing lesions seen on breast screening mammograms should be excised. Eur J Surg Oncol 2005;31:1125-1128.
  84. Oyama T, Koerner FC. Noninvasive papillary proliferations. Semin Diagn Pathol 2004;21:32-41.
  85. MacGrogan G, Tavassoli FA. Central atypical papillomas of the breast: a clinicopathological study of 119 cases. Virchows Arch 2003;443:609-617.
  86. Agoff SN, Lawton TJ. Papillary lesions of the breast with and without atypical ductal hyperplasia: can we accurately predict benign behavior from core needle biopsy? Am J Clin Pathol 2004;122:440-443.
  87. Ivan D, Selinko V, Sahin AA et al. Accuracy of core needle biopsy diagnosis in assessing papillary breast lesions: histologic predictors of malignancy. Mod Pathol 2004;17:165-171.
  88. Ali-Fehmi R, Carolin K, Wallis T et al. Clinicopathologic analysis of breast lesions associated with multiple papillomas. Hum Pathol 2003;34:234-239.
  89. Krieger N, Hiatt RA. Risk of breast cancer after benign breast diseases. Variation by histologic type, degree of atypia, age at biopsy, and length of follow-up. Am J Epidemiol 1992;135:619-631.
  90. Levshin V, Pikhut P, Yakovleva I et al. Benign breast lesions and cancer of the breast. Eur J Cancer Prev 1998;7(suppl 1):S37-S40.
  91. Page DL, Salhany KE, Jensen RA et al. Subsequent breast carcinoma risk after biopsy with atypia in breast papilloma. Cancer 1996;78:258-266.
  92. Pacilli M, Sebire NJ, Thambapillai E et al. Juvenile papillomatosis of the breast in a male infant with Noonan syndrome, cafe' au lait spots, and family history of breast carcinoma. Pediatr Blood Cancer 2005;45:991-993.
  93. Bazzocchi F, Santini D, Martinelli G et al. Juvenile papillomatosis (epitheliosis) of the breast: a clinical and pathologic study of 13 cases. Am J Clin Pathol 1986;86:745-748.
  94. Rosen PP, ed. Chapter 39. Breast tumors in children. In: Rosen's Breast Pathology, Second Edition. Philadelphia: Lippincott Williams & Wilkins, 2001:729-748.
  95. Haj M, Weiss M, Herskovits T. Diabetic sclerosing lymphocytic lobulitis of the breast. J Diabetes Complications 2004;18:187-191.
  96. Camuto PM, Zetrenne E, Ponn T. Diabetic mastopathy: a report of 5 cases and a review of the literature. Arch Surg 2000;135:1190-1193.
  97. Baratelli GM, Riva C. Diabetic fibrous mastopathy: sonographic-pathologic correlation. J Clin Ultrasound 2005;33:34-37.
  98. Castro CY, Whitman GJ, Sahin AA. Pseudoangiomatous stromal hyperplasia of the breast. Am J Clin Oncol 2002;25:213-216.
  99. Pruthi S, Reynolds C, Johnson RE et al. Tamoxifen in the management of pseudoangiomatous stromal hyperplasia. Breast J 2001;7:434-439.
  100. Mercado CL, Naidrich SA, Hamele-Bena D et al. Pseudoangiomatous stromal hyperplasia of the breast: sonographic features with histopathologic correlation. Breast J 2004;10:427-432.
  101. El-Wakeel H, Umpleby HC. Systematic review of fibroadenoma as a risk factor for breast cancer. Breast 2003;12:302-307.
  102. Hughes LE, Mansel RE, Webster DJT. Aberrations of normal development and involution (ANDI): a new perspective on pathogenesis and nomenclature of benign breast disorders. Lancet 1987;2:1316-1319.
  103. Tavassoli FA, ed. Chapter 11. Biphasic tumors. In: Pathology of the Breast, Second Edition. Stamford, CT: Appleton & Lange, 1999:571-631.
  104. Kleer CG, Tseng MD, Gutsch DE et al. Detection of Epstein-Barr virus in rapidly growing fibroadenomas of the breast in immunosuppressed hosts. Mod Pathol 2002;15:759-764.
  105. Moore T, Lee AHS. Expression of CD34 and bcl-2 in phyllodes tumours, fibroadenomas and spindle cell lesions of the breast. Histopathology 2001;38:62-67.
  106. Franco N, Arnould L, Mege F et al. Comparative analysis of molecular alterations in fibroadenomas associated or not with breast cancer. Arch Surg 2003;138:291-295.
  107. Valdes EK, Boolbol SK, Cohen JM et al. Malignant transformation of a breast fibroadenoma to cystosarcoma phyllodes: case report and review of the literature. Am Surg 2005;71:348-353.
  108. Geisler DP, Boyle MJ, Malnar KF et al. Phyllodes tumors of the breast: a review of 32 cases. Am Surg 2000;66:360-366.
  109. Chen WH, Cheng SP, Tzen CY et al. Surgical treatment of phyllodes tumors of the breast: retrospective review of 172 cases. J Surg Oncol 2005;91:185-194.
  110. Carter BA, Page DL, Schuyler P et al. No elevation in long-term breast carcinoma risk for women with fibroadenomas that contain atypical hyperplasia. Cancer 2001;92:30-36.
  111. Shabtai M, Saavedra-Malinger P, Shabtai EL et al. Fibroadenoma of the breast: analysis of associated pathological entities--a different risk marker in different age groups for concurrent breast cancer. Isr Med Assoc J 2001;3:813-817.
  112. Graf O, Helbich TH, Fuchsjaeger MH et al. Follow-up of palpable circumscribed noncalcified solid breast masses at mammography and US: can biopsy be averted? Radiology 2004;233:850-856.
  113. Wechselberger G, Schoeller T, Piza-Katzer H. Juvenile fibroadenoma of the breast. Surgery 2002;132:106-107.
  114. Lanng C, Eriksen BO, Hoffmann J. Lipoma of the breast: a diagnostic dilemma. Breast 2004;13:408-411.
  115. Reeves ME, Tabuenca A. Lactating adenoma presenting as a giant breast mass. Surgery 2000;127:586-588.
  116. Baker TP, Lenert JT, Parker J et al. Lactating adenoma: a diagnosis of exclusion. Breast J 2001;7:354-357.
  117. Soo MS, Dash N, Bentley R et al. Tubular adenomas of the breast: imaging findingswithhistologiccorrelation.AJR Am J Roentgenol 2000;174:757-761.
  118. Montemarano AD, Sau P, James WD. Superficial papillary adenomatosis of the nipple: a case report and review of the literature. J Am Acad Dermatol 1995;33:871-875.
  119. Gatti G, Mazzarol G, Simsek S et al. Breast hamartoma: a case report. Breast Cancer Res Treat 2005;89:145-147.
  120. Herbert M, Sandbank J, Liokumovich P et al. Breast hamartomas: clinicopathological and immunohistochemical studies of 24 cases. Histopathology 2002;41:30-34.
  121. Tse GMK, Law BKB, Ma TKF et al. Hamartoma of the breast: a clinicopathological review. J Clin Pathol 2002;55:951-954.
  122. Montagnese MD, Roshong-Denk S, Zaher A et al. Granular cell tumor of the breast. Am Surg 2004;70:52-54.
  123. Ilvan S, Ustundag N, Calay Z et al. Benign granular-cell tumour of the breast. Can J Surg 2005;48:155-156.
  124. Balzan SMP, Farina PS, Maffazzioli L et al. Granular cell breast tumour: diagnosis and outcome. Eur J Surg 2001;167:860-862.
  125. Chetty R, Kalan MR. Malignant granular cell tumor of the breast. J Surg Oncol 1992;49:135-137.
  126. Adeniran A, Al-Ahmadie H, Mahoney MC et al. Granular cell tumor of the breast: a series of 17 cases and review of the literature. Breast J 2004;10:528-531.

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