Axillary lymphadenopathy

Alternative names
Lump in the armpit; Localized lymphadenopathy - armpit; Armpit lump; Axillary lymphs enlarged; Lymph nodes enlarged-axillary; Axillary abscess

Definition
An armpit lump refers to enlargement of one or more lymph nodes in the armpit(s).

Considerations
Lumps in the armpit (axilla) have various causes. Cysts and superficial infections in the skin of the armpit may follow shaving or use of antiperspirants (as opposed to deodorants). This occurs most frequently in adolescents just beginning to shave. Subcutaneous (under the skin) abscesses may also produce large, painful lumps in the armpit.

Lumps may be produced by lymph nodes enlarged due to bacterial infections, viral infections, antigenic stimulation (as from vaccinations), and malignancy. A breast self-examination should always include the armpit because breast cancer can enlarge the armpit lymph nodes even when the breast itself seems perfectly normal.

Lymph nodes are filters that can catch malignant tumor cells or infectious organisms. When they do, lymph nodes increase in size and are easily felt.

Common Causes

     
  • bacterial       o localized infection, possibly somewhere in the arm or breast draining into the glands of the armpit, or infection within the armpit itself       o cat scratch disease       o ascending lymphangitis       o lymphadenitis, lymphangitis  
  • viral       o infectious mononucleosis       o chickenpox       o herpes zoster (shingles)       o HIV disease (AIDS)  
  • malignant       o Hodgkin’s lymphoma       o non-Hodgkin’s lymphoma       o leukemia  
  • fungal       o sporotrichosis  
  • antigenic       o smallpox vaccination       o typhoid vaccine       o measles, mumps, rubella vaccine (rare)       o allergic reaction possibly caused by sulfa drugs, iodine, or penicillin  
  • other       o lipomas (harmless fatty growths)       o benign (harmless) cyst       o normal breast tissue (breast tissue extends into the armpit area)

Home Care
Check with your health care provider to determine the nature of the lump.

For a lump in the armpit caused by an infected, painful gland, follow the instructions about the proper treatment for the underlying infection.

A lump in the armpit caused by a generalized viral infection will eventually disappear without therapy. A lump in the armpit caused by an allergic reaction will go away after the provoking substance is removed. No treatment is necessary for a lump in the armpit caused by normal breast tissue, and usually no treatment is necessary for a cyst.

A lump in the armpit caused by a lipoma (fatty growth) is harmless, unless it grows so large that it causes discomfort.

For a lump in the armpit caused by a malignancy, follow the appropriate cancer treatment recommended by a doctor.

Call your health care provider if

     
  • there is any unexplained armpit lump(s). Do not try to diagnose lumps without professional help.

What to expect at your health care provider’s office
Your doctor will perform a physical examination and ask medical history questions about the armpit lump, such as:

     
  • time pattern       o When did you first notice the lump?       o Is it getting better, worse, or staying the same?  
  • aggravating factors       o Are you breast feeding?       o Have you noticed any factors that make it worse?  
  • other       o What other symptoms are also present?       o Is the lump painful?

The physical examination may include palpation (gently pressing the nodes) of the lymph system.

Testing depends on what is found during the physical examination. Diagnostic tests that may be performed include:

     
  • liver function tests  
  • renal function tests  
  • lymph node biopsy  
  • platelet count  
  • routine blood work (such as a CBC)  
  • X-ray of the chest  
  • liver-spleen scan  
  • mammogram

Johns Hopkins patient information

Last revised: December 4, 2012
by Amalia K. Gagarina, M.S., R.D.

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All ArmMed Media material is provided for information only and is neither advice nor a substitute for proper medical care. Consult a qualified healthcare professional who understands your particular history for individual concerns.