Two prior unsuccessful antidepressant trials usually spell treatment failure with a third, new research suggests. In this scenario, remission rates are less than 20 percent.

The findings of the study, the Sequenced…

A study carried out by German researchers has failed to show that a popular antidepressant, paroxetine, causes congenital abnormalities if taken by pregnant women, the 22nd…

The Food and Drug Administration (FDA) has approved Wellbutrin XL for prevention of major depressive episodes in patients with a history of seasonal affective disorder (SAD).

This is…

A new study should help alleviate any concern over a link between the use of certain antidepressants and suicide.

A new class of drugs called selective serotonin reuptake inhibitors (SSRI) have been…

Europe’s medicine watchdog said on Tuesday that Prozac could be used to treat children aged eight years and over.

Despite controversy over giving antidepressants to adolescents, the European Medicines Agency…

Among men with major depression, treatment with Cymbalta is associated with less worsening of sexual function than is treatment with Lexapro, investigators reported this week at the American Psychiatric Association…

Researchers at Cold Spring Harbor Laboratory on Long Island have identified which among several different kinds of cells in the brain is the chief target of the widely…

According to Canadian researchers seniors who are prescribed antidepressants such as Prozac, Paxil and Zoloft are almost five times more likely to commit suicide during the first month on…

A new study shows that when patients with major depression fail to respond to a course of Celexa (citalopram) or cannot tolerate its side effects, approximately one third of those…

Whether depressed patients will respond to an antidepressant depends, in part, on which version of a gene they inherit, a study led by scientists at the National Institutes…

Until recently, antidepressants - especially selective serotonin reuptake inhibitors (SSRIs) - were considered fairly safe for pregnant women.

But late last year, citing evidence from…

Patients with coronary artery disease may be at increased risk of death while using antidepressant drugs, according to the results of an observational study reported at the American Psychosomatic…

A University of California, San Diego (UCSD) School of Medicine collaborative study with Boston University’s Slone Epidemiology Center found an increased risk of persistent pulmonary hypertension (PPHN) in newborns of mothers who used…

The number of adverse reactions reported by UK doctors to the antidepressant paroxetine - often know by its brand name Seroxat - rose by 61 per cent…

Supplementing the antidepressant Wellbutrin (bupropion) with a reward system called “contingency management” (CM) can further reduce cocaine use in addicted subjects maintained with methadone, new research shows.

With CM,…

Infants who are exposed to selective serotonin reuptake inhibitors (SSRIs), such as Prozac and Zoloft, in the womb are at risk for developing neonatal abstinence syndrome (NAS), a withdrawal disorder characterized…

Antidepressants like Prozac and Zoloft, which affect a brain chemical called serotonin, may also influence the body’s immune system, new research suggests.

Prozac and Zoloft belong to a group of drugs called…

The antidepressant Prozac (fluoxetine) may help relieve certain emotional disturbances in patients who’ve suffered a stroke, Korean researchers report. As senior investigator Dr. Jong S. Kim told Reuters Health, Prozac significantly…

Suicidal behavior among adults taking antidepressants drops almost as soon as they begin medication, researchers said on Sunday in findings that experts said confirm their effectiveness in older patients.

The…

High levels of sugar in the blood, also known as hyperglycemia, is a common finding in individuals taking atypical antipsychotics who are thought to have normal blood sugar levels.

Over a…

The antidepressant citalopram (Celexa) may be used cautiously in pregnant women, according to a report from Canada. The researchers report no excess birth defect risk, although an increased risk of…

The FDA warned doctors today that preliminary results implicate the antidepressant Paxil (paroxetine) with an increased risk of birth defects.

The FDA informed doctors that results of new studies suggest that…

Benzodiazepines
Benzodiazepine dosing is generally titrated to maximize symptom relief while minimizing side effects and the potential for abuse. No routine monitoring is required; although serum drug levels can be obtained, they are…

Benzodiazepines

The selection of a benzodiazepine should be based on an understanding of potency, rate of onset, route of metabolism, effective half-life, and clinically proven effectiveness. Although all benzodiazepines appear to function by…