Although most studies have reported a higher risk of depression in people with epilepsy as compared with normal controls, almost all studies (with a few exceptions such as Blumer 2002) report no difference…

Treatment of psychiatric disorders in epilepsy is largely opinion-led, with little evidence from systematic randomized control trials (Krishnamoorthy 2003).

Pre-ictal and ictal depression do not usually require treatment; an improvement in seizure…

Depression in epilepsy is multifactorial in nature and has been shown to be influenced by a number of factors.

Gender
In contrast to the increased prevalence of depression in females,…

Forced normalization
In the 16th century, Cardenus (Whitwell 1936) wrote about a case of melancholia alternating with epilepsy, describing what is possibly the first case of forced normalization associated with epilepsy.…

Depression is a common and important accompaniment of epilepsy.  Depression in epilepsy is phenomenologically different from the usual forms of depression and it is essential that treating physicians assess for…