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A new study shows that when patients with major depression fail to respond to a course of Celexa (citalopram) or cannot tolerate its side effects, approximately one third of those…

New research from the University of North Carolina at Chapel Hill School of Medicine describes how cells recover from heat, cold and other stressful conditions.

The findings also…

Using new technology and a unique approach, Binghamton University researchers are hoping to help children with autism spectrum disorders (ASD) deal with their most common and problematic areas of…

Older women who say talk shows and soap operas are their favorite TV programs tend to score more poorly on tests of memory, attention and other cognitive skills,…

Young adolescents who own t-shirts, hats and other merchandise with an alcohol brand name on it are more likely to begin drinking than kids who do not own these items,…

Incontinence Associated With Higher Risk of Depression in Women

Incontinence is associated with nearly double the risk of depression for women with the problem than those without, according…

Parents who have cared for a dying child at home may be at higher risk of suicide after the child dies, by overdosing on the powerful painkillers used to ease the…

Whether depressed patients will respond to an antidepressant depends, in part, on which version of a gene they inherit, a study led by scientists at the National Institutes…

Problem gambling runs in families according to a University of Iowa study published online Feb. 24 in the journal Psychiatry Research.

The study also found an excess of alcoholism, drug disorders and…

A new review of studies found few documented attempts, but encouraging results in the effort to improve the health and medical care of patients with mental illness.

An…

A Johns Hopkins study of more than 1,700 patients with schizophrenia hospitalized for medical or surgical care unrelated to their mental disorder shows they are at least…

Researchers have found that a common anticonvulsant drug improved cognitive function and appeared to restore nerve cells in the brains of patients with HIV-related dementia. The results of…

Even when heart disease patients can pass stress tests done on a treadmill or with chemical stressors after treatment, their hearts may still suffer silent ischemia during mental stress,…

Contrary to popular myth, expressing anger in the moment is not healthy.

According to a new book, Getting Control of Your Anger: A Clinically Proven, Three-Step Plan for Getting…

When mothers experience symptoms of depression after the birth of their children they are less likely to breastfeed, play with, read to or…

The impulse control disorder drug nalmefene, which has previously been shown to be effective for alcohol dependence, may also be effective for pathological gambling, according to a study.

“Pathological gambling is a…

Until recently, antidepressants - especially selective serotonin reuptake inhibitors (SSRIs) - were considered fairly safe for pregnant women.

But late last year, citing evidence from…

Some people are more than twice as likely to become depressed as others, given similar circumstances, according to landmark research from Brain Sciences University…

Young women with a history of depression in adolescence are more likely than their peers to become victims of abuse from a boyfriend or husband, new research suggests.

Bipolar Depressive Subtypes, Other Clinical Factors, and Treatment Response
Although pharmacotherapy with lithium is an effective treatment for many patients with bipolar disorder, Maj and colleagues (1989)…

Conclusions
Treatment resistance is not a unitary phenomenon but in mood disorders reflects issues of diagnostic subtypes, comorbidity, and treatment adequacy, augmentation, and alternatives. In clinical practice, therefore, it is not…

Treatment-Resistant Unipolar Depression

Appendix: Multiphase Treatment Strategy for Bipolar Disorder

See

Treatments to Control Cycling
As noted earlier, for about 90% of bipolar disorders, recurrence rather than persistence of acute episodes is the primary problem in psychopharmacological management. During the past two decades…

Treatment of Bipolar Depression
The algorithm presented for treatment-resistant bipolar depression (